2018, Cilt 10, Sayı 1, Sayfa(lar) 011-015
Data Evaluation İn Patients Undergoing Radical Prostatectomy İn Terms Of Compatibility With Partin Tables
Oğuzhan Parlakkılıç1, Egemen Avcı2, İnanç Yılmaz3, Yılmaz Salman4, Fatih Kurtuluş1, Mete Çek5
1Kolan International Şişli Hastanesi, İstanbul, Türkiye
2Memorial Ataşehir Hastanesi, İstanbul, Türkiye
3Özel Çorlu Vatan Hastanesi, Çorlu/ Tekirdağ, Türkiye
4Sancaktepe Şehit Prof. Dr. İlhan Varank EAH, İstanbul/ Türkiye
5Trakya Üniversitesi Tıp Fakültesi Üroloji Kliniği, Edirne/ Türkiye
Keywords: Prostate, cancer, Partin, nomograms, radical, prostatectomy

Aims: In this study, we aimed to evaluate the preoperative and postoperative data of patients with prostate cancer (Pca) who underwent radical prostatectomy operations in our clinic and to compare them with the Partin Tables.

Materials and Methods: 152 patients with a mean age of 66 (47-75) who underwent radical retropubic prostatectomy for Pca were included in the study. Patients’ preoperative clinical stages, biopsy Gleason scores and total PSA values were recorded. pelvic lymph nodes removed during the operation were examined microscopically for the presence of micrometastatic cancer. Operative specimen (prostate and vesicular seminalis) was prepared for pathological examination. The association of patient’s data with Partin Tables was assessed by Receiver Operating Characteristics (ROC) analysis.

Results: In T1c and T2a stage, lymph node positivity was not observed in the pathology specimen. In T1c stage, organ confined disease was 64% whereas in T2c stage organ confined disease was 27%. There is no lymph node and seminal vesicle positivity in the Gleason 6 group. In patients with Gleason 8-10, extracapsular extension is 66% and lymph node positivity is 33%. In the entire population, patients having PSA levels 0-2.5, 2.5-4 and 6.1-10.0 were 4%,10% and 8% respectively. Patients with PSA levels between 4.1- 6.0 were 28%, and those over 10 make up 50%. The Area Under Curve (AUC) values were 0.674 (p <0.001), 0.741 (p <0.001), 0.842 (p <0.005) for extracapsular extension, seminal vesicle involvement and lymph node involvement respectively.

Conclusion: Current patient findings were statistically consistent with Partin nomograms, and it was concluded that the Partin Tables are also applicable for updated patient populations.