2018, Cilt 10, Sayı 1, Sayfa(lar) 032-038
The Role And Importance of Mean Platellet Volume in Diagnosis of Subclinic Intraamniotic Infection And in Follow Up Premature Rupture of Membranes
Mustafa Sağlam1, Abdullah Boztosun1, Şehmus Pala2
1Akdeniz Üniversitesi Tıp Fakültesi, Kadın Hastalıkları ve Doğum, Antalya, Turkiye
2Fırat Üniversitesi Tıp Fakültesi, Kadın Hastalıları ve Doğum Anabilim Dalı, Elazığ, Turkiye
Keywords: PPROM, MPV, subclinic intraamniotic infection

Aim: This study was carried out in order to determine the role and importance of MPV for diagnosis and follow up of subclinical infections in PPROM and to compare the values of ProCT, CRP and WBC.

Methods: The patient group consists of 38 patients diagnosed for PPROM and control group consists of 43 healthy pregnant women between 24 and 34 gestational weeks. WBC, ProCT, CRP and MPV values of patients at diagnosis, delivery and values of women in control groupwere assessed and compared. The placental pathology reports of patient group were examined. WBC, ProCT, CRP and MPV values of those having chorioamnionitis were compared.

Results: In study group, the WBC (17.01 ± 4.82), CRP (1.15 ± 0.74), and ProCT (0.08 ± 0.05) values measured before the delivery were significantly higher than those measured at the moment of diagnosis. Of the study group, the WBC (11.97 ± 2.59) and CRP (0.48 ± 0.29) values measured at the moment of diagnosis were significantly higher than those of control group. Prenatal WBC (17.01 ± 4.82), CRP (1.15 ± 0.74) and ProCT (0.08 ± 0.05) values of patients were statistically significantly higher than those of control group. CRP (1.73±0.67) values of patients with chorioamnionitis were higher than those of patients having no chorioamnionitis. There was no significant relationship between MPV values of the groups.

Conclusion: WBC, CRP and ProCT can be interpreted to be capable of diagnostically predicting the intrauterine infection. No statistically significant relationship was found between MPV, diagnosis and sub-clinic infection in PROM.