2019, Cilt 11, Sayı 1, Sayfa(lar) 005-009
Retrospective comparison of embryo morphokinesis between cases of teratozoospermia and normozoospermia in IVF cycles followed by time-lapse imaging system
Özge Berberoğlu1, Mehmet Cıncık2, Belgin Selam3
1Maltepe Üniversitesi, Sağlık Bilimleri Enstitüsü, Istanbul, Türkiye
2Maltepe Üniversitesi, Tıp Fakültesi, Histoloji ve Embriyoloji Anabilim Dalı, Istanbul, Türkiye
3Acıbadem Mehmet Ali Aydınlar Üniversitesi, Tıp Fakültesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, Istanbul, Türkiye
Keywords: Sperm morphology, embryo, early cleavage
Doi: 10.35514/mtd.2019.1

Aim: To investigate the correlation of embryo quality, fertilization and pregnancy rates with sperm morphology in ICSI (Intracytoplasmic sperm injection) cycles. Also, to compare early cleavage percentage with the sperm morphology.

Methods: 60 infertile couples were included in this retrospective study. Azoospermic patients were not included in the study and female age was kept below 40. Sperm preparates were stained with hematoxylin method and morphology was evaluated according to Kruger criteria. Sperm morphology > 4% was accepted as normal. Fertilization was accepted as 2 pronuclei between 16th and 18th hours; embryo quality was classified as grade 1, 2 ,3 depending on the morphology and uniform distribution of blastomeres, and fragmentation on the third day. Fertilization, morphokinesis, embryo quality, early cleavage and pregnancy rates were evaluated according to sperm morphology in the current study.

Results: Study group with teratozoospermi (normal morphology <%4, n=30) and control group with normozoospermi (normal morphology ≥%4, n=30; kontrol grubu) were evaluated among 60 patients. Fertilization rates were 53% and 40% in the normal and abnormal groups, respectively (p>0,01). Embryo quality were similar among both groups according to grade 1, grade 2 and grade 3 embryos (p>0,01). There was no significant correlation between the early cleavage and sperm morphology (p>0,01). Pregnancy rates were similar in both groups (45% and 55% in study and control groups, respectively (p>0,01).

Conclusion: There is no significant relationship between sperm morphology and fertilization, , embryo quality, early cleavage and pregnancy rates in the current study