To investigate the correlation of embryo quality, fertilization and
pregnancy rates with sperm morphology in ICSI (Intracytoplasmic
sperm injection) cycles. Also, to compare early cleavage percentage
with the sperm morphology.
Methods: 60 infertile couples were included in this retrospective
study. Azoospermic patients were not included in the study and
female age was kept below 40. Sperm preparates were stained with
hematoxylin method and morphology was evaluated according to
Kruger criteria. Sperm morphology > 4% was accepted as normal.
Fertilization was accepted as 2 pronuclei between 16th and 18th
hours; embryo quality was classified as grade 1, 2 ,3 depending
on the morphology and uniform distribution of blastomeres,
and fragmentation on the third day. Fertilization, morphokinesis,
embryo quality, early cleavage and pregnancy rates were evaluated
according to sperm morphology in the current study.
Results: Study group with teratozoospermi (normal morphology
<%4, n=30) and control group with normozoospermi (normal
morphology ≥%4, n=30; kontrol grubu) were evaluated among
60 patients. Fertilization rates were 53% and 40% in the normal
and abnormal groups, respectively (p>0,01). Embryo quality were
similar among both groups according to grade 1, grade 2 and
grade 3 embryos (p>0,01). There was no significant correlation
between the early cleavage and sperm morphology (p>0,01).
Pregnancy rates were similar in both groups (45% and 55% in
study and control groups, respectively (p>0,01).
Conclusion: There is no significant relationship between sperm
morphology and fertilization, , embryo quality, early cleavage and
pregnancy rates in the current study