2011, Cilt 3, Sayı 1, Sayfa(lar) 021-027
The Effects of Diabetes Mellitus and Obesity to Pelvic Organ Prolapse in Postmenopausal Women
Hakan COKSUER, M.D.1, Berna HALİLOĞLU, M.D.2, Mutlu ERCAN, M.D.3, Mesut KOSE, M.D.4, Uğur KESKİN, M.D.3,İbrahim ALANBAY, M.D.3, Emre Karaşahin, M.D.3, Canan KABACA, M.D.5, Ateş KARATEKE, M.D.5
1Dumlupınar University, Faculty of Medicine, Department of Obstetrics and Gynecology, Kutahya, Turkey
2Maltepe University, Faculty of Medicine, Department of Obstetrics and Gynecology, Istanbul, Turkey
3Gulhane Military Medical Academy, Department of Obstetrics and Gynecology, Ankara, Turkey
4Afyonkarahisar Women and Children's Hospital, Department of Obstetrics and Gynecology, Afyonkarahisar-Turkey
5Zeynep Kamil Women and Children's Hospital, Department of Obstetrics and Gynecology, Uskudar Istanbul-Turkey
Keywords: cystocele, diabetes mellitus, obesity, pelvic organ prolapse, rectocele and uterine prolapse

Objective: We aim to evaluate the effect of diabetes and obesity on pelvic organ prolapse (POP) in postmenopausal women.

Methods: 104 women with POP, ages 49 to 79 were divided as group I (non diabetic-non obese), group II (non obese-diabetic), group III (obese-non diabetic) and group IV (obese-diabetic). For each group, presence of uterine prolapse, cystocele and rectocele using POP Quantification (POP-Q) system were assessed.

Results: Obesity and diabetes mellitus (DM) were associated with progression in cystocoele, rectocele and uterine prolapse compared with healthy women (p<0.001). Uterine prolapse stages of the obesity groups were also significantly higher than in the diabetic group (p<0.001).

Conclusions: Obesity and DM seem to be risk factors for POP. However, obesity as a modifiable risk factor has more effect on developing uterine prolapse than diabetes and it is important for developing new therapy strategies.